Junhyong Kim

junhyong Kim headshot

Faculty Advisory Board MemberPatricia M. Williams Term Professor and Chair, Biology; Co-Director, Penn Program in Single Cell Biology; Adjunct Professor, Computer and Information Science

Junhyong Kim is primarily a Systems Biologist and works at the interface of mathematical and computational biology, genomics, and evolutionary biology with a focus on neuro-cell biology. He uses quantitative models, statistical analyses, and collects genome-scale data to ask questions about mechanisms of cell function and their evolution. In particular, he is interested in theoretical structures of problems such as the mathematical structure of biological models, the architecture of temporal control for cellular processes, and the theory of biological dynamics. Working on theoretical problems is not limited to pen-and-pencils and his lab gathers data and tests hypotheses in the wet-lab and also develops new genomic technologies. A key technological expertise in his lab is single cell analysis, including RNA sequencing from single cells and bio-photonic techniques. In recent years, he have been focused on the mammalian neurons as an empirical system of study. Here, he is interested in RNA dynamics that establish cell phenotypes, variation of RNA states associated with single cell function, systems biology of individual synapses, and evolution of central nervous systems via modulation of neurons.